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Hydroquinone

CAS: 123-31-9

How can this chemical affect my health?

Acute (Short Term) EffectsData sources

Toxic To Humans & Animals priority 7
Toxic to Humans & Animals – Can be fatal on contact, ingestion or inhalation for humans and other mammals.
Irritates The Eyes priority 3
Irritates the Eyes – Can cause irritation or serious damage to the eye.
Irritates The Skin priority 7
Irritates the Skin – Can cause irritation or serious damage to the skin.

Data sources:

Direct Hazard » Toxic to Humans & Animals

These sources refer directly to this chemical:

  • Extremely Hazardous Substances
    Extremely Hazardous Substances - EPCRA Section 302
    US Environmental Protection Agency (US EPA)
  • H302 - Harmful if swallowed
    Regulation on the Classification, Labelling and Packaging of Substances and Mixtures (CLP) Annex 6 Table 3-1 - GHS Hazard code criteria
    European Union / European Commission (EU EC)
  • 6.1B (oral) - Acutely toxic
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • H302 - Harmful if swallowed
    Australia - GHS
    Safe Work Australia
  • H302 - Harmful if swallowed
    Malaysia - GHS
    Malaysia Department of Occupational Safety and Health
  • Acute toxicity (oral) - Category 4
    Japan GHS Classifications
    Government of Japan
  • Acute toxicity (oral) - Category 4 [H302 - Harmful if swallowed]
    Korea GHS Classification and Labelling for Toxic Chemicals
    Republic of Korea - National Institute of Environmental Research (NIER)
  • Class D1B - Toxic material causing immediate and serious toxic effects
    WHMIS-SIMDUT: Controlled Products Classifications
    Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
  • H312 - Harmful in contact with skin (unverified)
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Irritates the Eyes

These sources refer directly to this chemical:

  • H318 - Causes serious eye damage
    Regulation on the Classification, Labelling and Packaging of Substances and Mixtures (CLP) Annex 6 Table 3-1 - GHS Hazard code criteria
    European Union / European Commission (EU EC)
  • H318 - Causes serious eye damage
    Australia - GHS
    Safe Work Australia
  • Serious eye damage / eye irritation - Category 1
    Japan GHS Classifications
    Government of Japan
  • H318 - Causes serious eye damage
    Malaysia - GHS
    Malaysia Department of Occupational Safety and Health
  • 8.3A - Corrosive to ocular tissue (Cat. 1)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)

Direct Hazard » Irritates the Skin

These sources refer directly to this chemical:

  • 6.3A - Irritating to the skin (Cat. 2)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • H315 - Causes skin irritation (unverified)
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Chronic (Long Term) EffectsData sources

Cancer priority 7
Cancer – Can cause or increase the risk of cancer.
Endocrine Disruption priority 3
Endocrine Disruption – Can interfere with hormone communication between cells which controls metabolism, development, growth, reproduction and behavior (the endocrine system).
Gene Damage priority 3
Gene Damage – Can cause or increase the rate of mutations, which are changes in genetic material in cells.
Sensitizes The Skin priority 4
Sensitizes the Skin – Can lead to allergic reactions on the skin.
Other Health Effects priority 4
Other Health Effects – Can cause serious damage on contact or ingestion.
Brain/nervous System Harm priority 7
Brain/Nervous System Harm – Can cause damage to the nervous system including the brain.

Data sources:

Direct Hazard » Cancer

These sources refer directly to this chemical:

  • Carcinogen Group 2 - Considered to be carcinogenic for man
    List of Substances with MAK & BAT Values & Categories
    MAK Commission of Germany (Deutsche Forschungsgemeinschaft)
  • Carcinogen Category 2 - Suspected human Carcinogen
    Classification, Labelling and Packaging Regulation (CLP) - Classification and Labelling Inventory - CMRs
    European Union / European Commission (EU EC)
  • H351 - Suspected of causing cancer
    Regulation on the Classification, Labelling and Packaging of Substances and Mixtures (CLP) Annex 6 Table 3-1 - GHS Hazard code criteria
    European Union / European Commission (EU EC)
  • H351 - Suspected of causing cancer
    Australia - GHS
    Safe Work Australia
  • Carcinogenicity - Category 2
    Japan GHS Classifications
    Government of Japan
  • Carcinogenicity - Category 2 [H351 - Suspected of causing cancer]
    Korea GHS Classification and Labelling for Toxic Chemicals
    Republic of Korea - National Institute of Environmental Research (NIER)
  • H351 - Suspected of causing cancer
    Malaysia - GHS
    Malaysia Department of Occupational Safety and Health
  • Group 3 - Agent is not classifiable as to its carcinogenicity to humans
    Monographs On the Evaluation of Carcinogenic Risks to Humans
    International Agency for Research on Cancer, World Health Organization (IARC)

Direct Hazard » Endocrine Disruption

These sources refer directly to this chemical:

  • Potential Endocrine Disruptor
    TEDX (The Endocrine Disruption eXchange) List of Potential Endocrine Disruptors
    The Endocrine Disruption Exchange (TEDX)

Direct Hazard » Gene Damage

These sources refer directly to this chemical:

  • Germ Cell Mutagen 3a
    List of Substances with MAK & BAT Values & Categories
    MAK Commission of Germany (Deutsche Forschungsgemeinschaft)
  • Mutagen - Category 2
    Classification, Labelling and Packaging Regulation (CLP) - Classification and Labelling Inventory - CMRs
    European Union / European Commission (EU EC)
  • H341 - Suspected of causing genetic defects
    Regulation on the Classification, Labelling and Packaging of Substances and Mixtures (CLP) Annex 6 Table 3-1 - GHS Hazard code criteria
    European Union / European Commission (EU EC)
  • Germ cell mutagenicity - Category 1B
    Japan GHS Classifications
    Government of Japan
  • H341 - Suspected of causing genetic defects
    Australia - GHS
    Safe Work Australia
  • H341 - Suspected of causing genetic defects
    Malaysia - GHS
    Malaysia Department of Occupational Safety and Health
  • 6.6B - Suspected human mutagens
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)

Direct Hazard » Sensitizes the Skin

These sources refer directly to this chemical:

  • Sensitizing Substance Sh - Danger of skin sensitization
    List of Substances with MAK & BAT Values & Categories
    MAK Commission of Germany (Deutsche Forschungsgemeinschaft)
  • H317 - May cause an allergic skin reaction
    Regulation on the Classification, Labelling and Packaging of Substances and Mixtures (CLP) Annex 6 Table 3-1 - GHS Hazard code criteria
    European Union / European Commission (EU EC)
  • Skin sensitizer - Category 1
    Japan GHS Classifications
    Government of Japan
  • Skin sensitization - Category 1 [H317 - May cause an allergic skin reaction]
    Korea GHS Classification and Labelling for Toxic Chemicals
    Republic of Korea - National Institute of Environmental Research (NIER)
  • 6.5B (contact) - Contact sensitisers (Cat. 1)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • H317 - May cause an allergic skin reaction
    Australia - GHS
    Safe Work Australia
  • H317 - May cause an allergic skin reaction
    Malaysia - GHS
    Malaysia Department of Occupational Safety and Health

Direct Hazard » Other Health Effects

These sources refer directly to this chemical:

  • Specific target organs/systemic toxicity following single exposure - Category 1
    Japan GHS Classifications
    Government of Japan
  • 6.9B (oral) - Harmful to human target organs or systems (Cat. 2)
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • Specific target organs/systemic toxicity following repeated exposure - Category 2
    Japan GHS Classifications
    Government of Japan

Direct Hazard » Brain/Nervous System Harm

These sources refer directly to this chemical:

  • Neurotoxic
    Developmental neurotoxicity of industrial chemicals, List of 201 Chemicals known to be neurotoxic in man
    Lancet: authors Philippe Grandjean & Phil Landrigan

Inherent HazardsData sources

Restricted List priority 5
Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.

Data sources:

Direct Hazard » Restricted List

These sources refer directly to this chemical:

  • CoHC List (non SVHC)
    Chemical Footprint Project - Chemicals of High Concern (CFP CoHC)
    Clean Production Action (CPA)
  • Ingredients that are Restricted for Use in Cosmetic Products
    Health Canada - Cosmetic Ingredient Hotlist
    Health Canada
  • HAPs subject to the Clean Air Act
    Clean Air Act Amendments of 1990 List of Hazardous Air Pollutants
    US Environmental Protection Agency (US EPA)

How does this chemical impact the environment?Data sources

Immediate Harm To Aquatic Ecosystems priority 3
Immediate Harm to Aquatic Ecosystems – A single exposure may result in severe biological harm or death to fish or other aquatic organisms.
Long-term Harm To Aquatic Ecosystems priority 7
Long-Term Harm to Aquatic Ecosystems – Long term exposure may result in irreversible harm to fish or other aquatic organisms.
Harmful To Land Ecosystems priority 3
Harmful to Land Ecosystems – Can cause harm to land based plants, animals or microorganisms.

Data sources:

Direct Hazard » Immediate Harm to Aquatic Ecosystems

These sources refer directly to this chemical:

  • H400 - Very toxic to aquatic life
    Regulation on the Classification, Labelling and Packaging of Substances and Mixtures (CLP) Annex 6 Table 3-1 - GHS Hazard code criteria
    European Union / European Commission (EU EC)
  • H400 - Very toxic to aquatic life
    Australia - GHS
    Safe Work Australia
  • Hazardous to the aquatic environment (acute) - Category 1
    Japan GHS Classifications
    Government of Japan
  • Hazardous to the aquatic environment (acute) - Category 1 [H400 - Very toxic to aquatic life]
    Korea GHS Classification and Labelling for Toxic Chemicals
    Republic of Korea - National Institute of Environmental Research (NIER)
  • H400 - Very toxic to aquatic life
    Malaysia - GHS
    Malaysia Department of Occupational Safety and Health
  • 9.1A (algal) - Very ecotoxic in the aquatic environment
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 9.1A (crustacean) - Very ecotoxic in the aquatic environment
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)
  • 9.1A (fish) - Very ecotoxic in the aquatic environment
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)

Direct Hazard » Long-Term Harm to Aquatic Ecosystems

These sources refer directly to this chemical:

  • Hazardous to the aquatic environment (chronic) - Category 1
    Japan GHS Classifications
    Government of Japan
  • H410 - Very toxic to aquatic life with long lasting effects (unverified)
    EU - Manufacturer REACH hazard submissions
    European Union / European Commission (EU EC)

Direct Hazard » Harmful to Land Ecosystems

These sources refer directly to this chemical:

  • 9.3A - Very ecotoxic to terrestrial vertebrates
    New Zealand HSNO Chemical Classifications
    New Zealand Environmental Protection Authority (NZ EPA)

What safer alternatives are available for this chemical?

Find case studies related to substitutions for this chemical in SubsPORT, the substitution support portal.

How am I likely to be exposed to this chemical?

Harmful if swallowed
Ingestion
Causes serious eye damage
Eye contact
May cause an allergic skin reaction
Skin contact

How can I protect myself from exposure to this chemical in the workplace?

glasses
Safety eyeware
suit
Protective clothing
gloves
Handle with gloves