Stronger effect / evidence




Weaker effect / evidence
Sodium hypochlorite
CAS: 7681-52-9
How can this chemical affect my health?
Acute (Short Term) EffectsData sources

Toxic to Humans & Animals – Can be fatal on contact, ingestion or inhalation for humans and other mammals.

Irritates the Skin – Can cause irritation or serious damage to the skin.

Irritates the Eyes – Can cause irritation or serious damage to the eye.
Data sources
Direct Hazard » Toxic to Humans & Animals
These sources refer directly to this chemical:
- FIFRA Registered PesticideUS EPA - OPP - Registered PesticidesUS Environmental Protection Agency (US EPA)
- H302 - Harmful if swallowed (unverified) [Acute toxicity (oral) - Category 4]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Irritates the Skin
These sources refer directly to this chemical:
- H314 - Causes severe skin burns and eye damage [Skin corrosion/irritation - Category 1A or 1B or 1C]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- Skin corrosion category 1CGHS - New ZealandNew Zealand Environmental Protection Authority (NZ EPA)
- H314 - Causes severe skin burns and eye damage [Skin corrosion/irritation - Category 1A or 1B or 1C]GHS - AustraliaSafe Work Australia
- H315 - Causes skin irritation (unverified) [Skin corrosion/irritation - Category 2]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H314 - Causes severe skin burns and eye damage (unverified) [Skin corrosion/irritation - Category 1A or 1B or 1C]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Direct Hazard » Irritates the Eyes
These sources refer directly to this chemical:
- H318 - Causes serious eye damage [Serious eye damage/eye irritation - Category 1]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- Serious eye damage category 1GHS - New ZealandNew Zealand Environmental Protection Authority (NZ EPA)
- H318 - Causes serious eye damage [Serious eye damage / eye irritation - Category 1]GHS - JapanGovernment of Japan
- H319 - Causes serious eye irritation (unverified) [Serious eye damage/eye irritation - Category 2A]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H318 - Causes serious eye damage (unverified) [Serious eye damage/eye irritation - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Chronic (Long Term) EffectsData sources

Asthma Trigger – Can result in high sensitivity so that small quantities trigger asthma, nose or sinus inflammation or other allergic reactions in the respiratory system.

Other Health Effects – Can cause serious damage on contact or ingestion.

Brain/Nervous System Harm – Can cause damage to the nervous system including the brain.
Data sources
Direct Hazard » Asthma Trigger
These sources refer directly to this chemical:
- Asthmagen (A) - expert listed pending AEOC reviewAOEC - AsthmagensAssociation of Occupational and Environmental Clinics (AOEC)
- Asthmagen (Rs) - sensitizer-inducedAOEC - AsthmagensAssociation of Occupational and Environmental Clinics (AOEC)
- Suspected asthmagen (R) - but does not meet AOEC criteria)AOEC - AsthmagensAssociation of Occupational and Environmental Clinics (AOEC)
Direct Hazard » Other Health Effects
These sources refer directly to this chemical:
- H335 or H336 [Specific target organs/systemic toxicity following single exposure - Category 3]GHS - JapanGovernment of Japan
- H335 - May cause respiratory irritation [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]GHS - AustraliaSafe Work Australia
- H335 - May cause respiratory irritation (unverified) [Specific target organ toxicity - single exposure; Respiratory tract irritation - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- Specific target organ toxicity - single exposure category 3 narcotic effectsGHS - New ZealandNew Zealand Environmental Protection Authority (NZ EPA)
Direct Hazard » Brain/Nervous System Harm
These sources refer directly to this chemical:
- H336 - May cause drowsiness or dizziness (unverified) [Specific target organ toxicity - single exposure; Narcotic effects - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
Inherent HazardsData sources

Reactive – May spontaneously ignite or explode on its own or in contact with water.

Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.
Data sources
Direct Hazard » Reactive
These sources refer directly to this chemical:
- Class C - Oxidizing materialsQuébec CSST - WHMIS 1988Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
- Class E - Corrosive materialsQuébec CSST - WHMIS 1988Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
- Class F - Dangerously reactive materialsQuébec CSST - WHMIS 1988Québec Workplace Health and Safety Commission (Commission de la santé et de la securite du travail (CSST))
- H272 - May intensify fire; oxidiser (unverified) [Oxidizing liquids; Oxidizing solids - Category 2 or 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H290 - May be corrosive to metals (unverified) [Corrosive to metals - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- Oxidising solids category 2GHS - New ZealandNew Zealand Environmental Protection Authority (NZ EPA)
Direct Hazard » Restricted List
These sources refer directly to this chemical:
- Substances selected for RMOA or hazard assessmentEU - PACT-RMOA SubstancesEuropean Union / European Commission (EU EC)
- AntimicrobialsGSPI - Six Classes of Problematic ChemicalsGreen Science Policy Institute (GSPI)
- Reportable ChemicalsMA Toxics Use Reduction Act (TURA) listed substancesMassachusetts Department of Environmental Protection
- Food Contact Chemicals Database Version 5.0Food Contact Chemicals Database (FCCdb)Food Packaging Forum
- Food Contact Chemicals of Concern List (FCCoCL)Food Contact Chemicals of Concern (FCCoCL)Food Packaging Forum
- Food Contact Chemicals of Concern List (FCCoCL) - TIER 3Food Contact Chemicals of Concern (FCCoCL)Food Packaging Forum
- FPF Priority Substance List from FCCdbFPF Priority Substance List from FCCdbFood Packaging Forum
- Food Packaging Forum Priority Substances ListGreenScreen Certified Standard for Food Service Ware RSLClean Production Action (CPA)
- TSCA Chemical Substance Inventory - ActiveTSCA Chemical Substance Inventory (Active-Inactive)US Environmental Protection Agency (US EPA)
How does this chemical impact the environment?Data sources

Immediate Harm to Aquatic Ecosystems – A single exposure may result in severe biological harm or death to fish or other aquatic organisms.

Long-Term Harm to Aquatic Ecosystems – Long term exposure may result in irreversible harm to fish or other aquatic organisms.
Data sources
Direct Hazard » Immediate Harm to Aquatic Ecosystems
These sources refer directly to this chemical:
- H400 - Very toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 1]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H400 - Very toxic to aquatic life [Hazardous to the aquatic environment (acute) - Category 1]GHS - JapanGovernment of Japan
- H400 - Very toxic to aquatic life (unverified) [Hazardous to the aquatic environment (acute) - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- Hazardous to the aquatic environment - acute category 1GHS - New ZealandNew Zealand Environmental Protection Authority (NZ EPA)
Direct Hazard » Long-Term Harm to Aquatic Ecosystems
These sources refer directly to this chemical:
- H410 - Very toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 1]EU - GHS (H-Statements) Annex 6 Table 3-1European Union / European Commission (EU EC)
- H410 - Very toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 1]GHS - JapanGovernment of Japan
- H410 - Very toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment (chronic) - Category 1]GHS - AustraliaSafe Work Australia
- H412 - Harmful to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 3]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H410 - Very toxic to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 1]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- H411 - Toxic to aquatic life with long lasting effects (unverified) [Hazardous to the aquatic environment (chronic) - Category 2]EU - Manufacturer REACH hazard submissionsEuropean Union / European Commission (EU EC)
- Hazardous to the aquatic environment - chronic category 1GHS - New ZealandNew Zealand Environmental Protection Authority (NZ EPA)
What safer alternatives are available for this chemical?
Find case studies related to substitutions for this chemical in SubsPORT, the substitution support portal.
How am I likely to be exposed to this chemical?

Skin contact

Eye contact
How can I protect myself from exposure to this chemical in the workplace?

Handle with gloves

Protective clothing

Safety eyeware