Stronger effect / evidence




Weaker effect / evidence
DIPROPYLHEPTYL PHTHALATE (DPHP)
CAS: 53306-54-0
How can this chemical affect my health?
Chronic (Long Term) EffectsData sources

Cancer – Can cause or increase the risk of cancer.

Asthma Trigger – Can result in high sensitivity so that small quantities trigger asthma, nose or sinus inflammation or other allergic reactions in the respiratory system.

Reproductive Harm – Can disrupt the male or female reproductive systems, changing sexual development, behavior or functions, decreasing fertility, or resulting in loss of the fetus during pregnancy.

Endocrine Disruption – Can interfere with hormone communication between cells which controls metabolism, development, growth, reproduction and behavior (the endocrine system).
Data sources
Direct Hazard » Cancer
These sources refer directly to this chemical:
- Carcinogen Group 3B - Evidence of carcinogenic effects but not sufficient for classificationMAKMAK Commission of Germany (Deutsche Forschungsgemeinschaft)
Direct Hazard » Reproductive Harm
These sources refer directly to this chemical:
- Repr. 2; H361 - Suspected of damaging fertility or the unborn child (modeled)DK-EPA - Danish Advisory ListDanish Environmental Protection Agency (DK-EPA)
Direct Hazard » Endocrine Disruption
These sources refer directly to this chemical:
- ECHA Endocrine disruptor assessment listECHA Endocrine DisruptorsEuropean Union / European Commission (EU EC)
- ED List II - Substances under evaluation for endocrine disruption under an EU legislationEndocrine Disruptor Lists (Danish EPA)Danish Environmental Protection Agency (DK-EPA)
Phthalates (orthophthalates) » Asthma Trigger
These sources refer to a group of compounds containing this chemical:
- Asthma - allergen, sensitizer - limited evidenceCHE - Toxicant DatabaseCollaborative on Health and the Environment (CHE)
- Asthma - irritant - limited evidenceCHE - Toxicant DatabaseCollaborative on Health and the Environment (CHE)
- Rhinitis – allergic - limited evidenceCHE - Toxicant DatabaseCollaborative on Health and the Environment (CHE)
Inherent HazardsData sources

Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.
Data sources
Phthalates (orthophthalates) » Restricted List
These sources refer to a group of compounds containing this chemical:
- Red List substance to avoid in Living Building Challenge V2.1 projectsLiving Building Challenge 2.1 - Red List of Materials & Chemicals (retired in 2014)International Living Future Institute (ILFI)
- Substance to avoid to fulfill LEED Pilot Credit 11USGBC - LEED Pilot CreditsUS Green Building Council (USGBC)
- Precautionary list of substances recommended for avoidanceP&W - Precautionary ListPerkins+Will (P+W)
- Substance to avoid to fulfill LEED Pilot Credit 54 Option 2USGBC - LEED Pilot CreditsUS Green Building Council (USGBC)
- Priority ChemicalsME DEP - Chemicals of High Concern and Priority ChemicalsMaine Department of Environmental Protection
- Prospective Red List substances to avoid in Living Building Challenge projectsLiving Building Challenge 3.0 - Red List of Materials & Chemicals (retiring December 31, 2024)International Living Future Institute (ILFI)
- Prohibited ChemicalsCredo Beauty's Restricted Substance ListCredo
- EDF Key chemicals of concern in food packaging and food handling equipmentEDF Key chemicals of concern in food packaging and food handling equipmentEnvironmental Defense Fund
Direct Hazard » Restricted List
These sources refer directly to this chemical:
- Candidate Chemical ListCA SCP - Candidate ChemicalsCalifornia Department of Toxic Substance Control (CA DTSC)
- Red List substances to avoid in Living Building Challenge V3 projectsLiving Building Challenge 3.0 - Red List of Materials & Chemicals (retiring December 31, 2024)International Living Future Institute (ILFI)
- Substances selected for RMOA or hazard assessmentEU - PACT-RMOA SubstancesEuropean Union / European Commission (EU EC)
- Bisphenols and PhthalatesGSPI - Six Classes of Problematic ChemicalsGreen Science Policy Institute (GSPI)
- Designated ChemicalCA DTSC - Biomonitoring California Chemical ListCalifornia Department of Toxic Substance Control (CA DTSC)
- Red List substances to avoid in Living Building Challenge V3.1 projectsLiving Building Challenge 3.1 - Red List of Materials & Chemicals (retiring December 31, 2024)International Living Future Institute (ILFI)
- Red List substances to avoid in Living Building Challenge V4.0 projectsLiving Building Challenge 4.0 - Red List of Materials & Chemicals - Effective April 1, 2023International Living Future Institute (ILFI)
- Food Contact Chemicals Database Version 5.0Food Contact Chemicals Database (FCCdb)Food Packaging Forum
- Ortho-PhthalatesGreenScreen Certified Standard for Food Service Ware RSLClean Production Action (CPA)
- TSCA Chemical Substance Inventory - ActiveTSCA Chemical Substance Inventory (Active-Inactive)US Environmental Protection Agency (US EPA)
- Ortho-phthalates (Silver-Gold)GreenScreen Certified Standard for Furniture & Fabrics Silver-Gold RSLClean Production Action (CPA)
- Ortho-phthalates (Silver-Gold)GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSLClean Production Action (CPA)
Ortho-phthalates - Biomonitoring Ca » Restricted List
These sources refer to a group of compounds containing this chemical:
- Priority ChemicalCA DTSC - Biomonitoring California Chemical ListCalifornia Department of Toxic Substance Control (CA DTSC)
What safer alternatives are available for this chemical?
Information on safer alternatives is currently fairly limited, and not easily accessible or linked to information on chemicals in the workplace. Where we have information on safer alternatives, ChemHAT will display links to existing case studies of safer alternatives for the chemical.