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Weaker effect / evidence

DIPROPYLHEPTYL PHTHALATE (DPHP)

CAS: 53306-54-0

How can this chemical affect my health?

Chronic (Long Term) EffectsData sources

Cancer, priority orange
Cancer – Can cause or increase the risk of cancer.
Asthma Trigger, priority yellow
Asthma Trigger – Can result in high sensitivity so that small quantities trigger asthma, nose or sinus inflammation or other allergic reactions in the respiratory system.
Reproductive Harm, priority gray
Reproductive Harm – Can disrupt the male or female reproductive systems, changing sexual development, behavior or functions, decreasing fertility, or resulting in loss of the fetus during pregnancy.
Endocrine Disruption, priority gray
Endocrine Disruption – Can interfere with hormone communication between cells which controls metabolism, development, growth, reproduction and behavior (the endocrine system).

Data sources

Direct Hazard » Cancer

These sources refer directly to this chemical:

  • Carcinogen Group 3B - Evidence of carcinogenic effects but not sufficient for classification
    MAK
    MAK Commission of Germany (Deutsche Forschungsgemeinschaft)

Direct Hazard » Reproductive Harm

These sources refer directly to this chemical:

  • Repr. 2; H361 - Suspected of damaging fertility or the unborn child (modeled)
    DK-EPA - Danish Advisory List
    Danish Environmental Protection Agency (DK-EPA)

Direct Hazard » Endocrine Disruption

These sources refer directly to this chemical:

  • ECHA Endocrine disruptor assessment list
    ECHA Endocrine Disruptors
    European Union / European Commission (EU EC)
  • ED List II - Substances under evaluation for endocrine disruption under an EU legislation
    Endocrine Disruptor Lists (Danish EPA)
    Danish Environmental Protection Agency (DK-EPA)

Phthalates (orthophthalates) » Asthma Trigger

These sources refer to a group of compounds containing this chemical:

  • Asthma - allergen, sensitizer - limited evidence
    CHE - Toxicant Database
    Collaborative on Health and the Environment (CHE)
  • Asthma - irritant - limited evidence
    CHE - Toxicant Database
    Collaborative on Health and the Environment (CHE)
  • Rhinitis – allergic - limited evidence
    CHE - Toxicant Database
    Collaborative on Health and the Environment (CHE)
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Inherent HazardsData sources

Restricted List, priority gray
Restricted List – This chemical is on a list from an authoritative body recommending that its use be avoided.

Data sources

Phthalates (orthophthalates) » Restricted List

These sources refer to a group of compounds containing this chemical:

  • Red List substance to avoid in Living Building Challenge V2.1 projects
    Living Building Challenge 2.1 - Red List of Materials & Chemicals (retired in 2014)
    International Living Future Institute (ILFI)
  • Substance to avoid to fulfill LEED Pilot Credit 11
    USGBC - LEED Pilot Credits
    US Green Building Council (USGBC)
  • Precautionary list of substances recommended for avoidance
    P&W - Precautionary List
    Perkins+Will (P+W)
  • Substance to avoid to fulfill LEED Pilot Credit 54 Option 2
    USGBC - LEED Pilot Credits
    US Green Building Council (USGBC)
  • Priority Chemicals
    ME DEP - Chemicals of High Concern and Priority Chemicals
    Maine Department of Environmental Protection
  • Prospective Red List substances to avoid in Living Building Challenge projects
    Living Building Challenge 3.0 - Red List of Materials & Chemicals (retiring December 31, 2024)
    International Living Future Institute (ILFI)
  • Prohibited Chemicals
    Credo Beauty's Restricted Substance List
    Credo
  • EDF Key chemicals of concern in food packaging and food handling equipment
    EDF Key chemicals of concern in food packaging and food handling equipment
    Environmental Defense Fund

Direct Hazard » Restricted List

These sources refer directly to this chemical:

  • Candidate Chemical List
    CA SCP - Candidate Chemicals
    California Department of Toxic Substance Control (CA DTSC)
  • Red List substances to avoid in Living Building Challenge V3 projects
    Living Building Challenge 3.0 - Red List of Materials & Chemicals (retiring December 31, 2024)
    International Living Future Institute (ILFI)
  • Substances selected for RMOA or hazard assessment
    EU - PACT-RMOA Substances
    European Union / European Commission (EU EC)
  • Bisphenols and Phthalates
    GSPI - Six Classes of Problematic Chemicals
    Green Science Policy Institute (GSPI)
  • Designated Chemical
    CA DTSC - Biomonitoring California Chemical List
    California Department of Toxic Substance Control (CA DTSC)
  • Red List substances to avoid in Living Building Challenge V3.1 projects
    Living Building Challenge 3.1 - Red List of Materials & Chemicals (retiring December 31, 2024)
    International Living Future Institute (ILFI)
  • Red List substances to avoid in Living Building Challenge V4.0 projects
    Living Building Challenge 4.0 - Red List of Materials & Chemicals - Effective April 1, 2023
    International Living Future Institute (ILFI)
  • Food Contact Chemicals Database Version 5.0
    Food Contact Chemicals Database (FCCdb)
    Food Packaging Forum
  • Ortho-Phthalates
    GreenScreen Certified Standard for Food Service Ware RSL
    Clean Production Action (CPA)
  • TSCA Chemical Substance Inventory - Active
    TSCA Chemical Substance Inventory (Active-Inactive)
    US Environmental Protection Agency (US EPA)
  • Ortho-phthalates (Silver-Gold)
    GreenScreen Certified Standard for Furniture & Fabrics Silver-Gold RSL
    Clean Production Action (CPA)
  • Ortho-phthalates (Silver-Gold)
    GreenScreen Certified Standard for Medical Supplies & Devices Silver-Gold RSL
    Clean Production Action (CPA)

Ortho-phthalates - Biomonitoring Ca » Restricted List

These sources refer to a group of compounds containing this chemical:

  • Priority Chemical
    CA DTSC - Biomonitoring California Chemical List
    California Department of Toxic Substance Control (CA DTSC)
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What safer alternatives are available for this chemical?

Information on safer alternatives is currently fairly limited, and not easily accessible or linked to information on chemicals in the workplace. Where we have information on safer alternatives, ChemHAT will display links to existing case studies of safer alternatives for the chemical.